• Users Online: 1474
  • Print this page
  • Email this page
RESEARCH PAPER
Year : 2020  |  Volume : 37  |  Issue : 1  |  Page : 4-10

Evaluation of the presence of neuropathy and pruritus in predialysis patients


1 Neurology Clinic, Tunceli Public Hospital, Tunceli, Turkey
2 Neurology Clinic, İstanbul Training and Research Hospital, İstanbul, Turkey
3 Nephrology Clinic, İstanbul Training and Research Hospital, İstanbul, Turkey

Correspondence Address:
Cansu Soylemez
Neurology Clinic, Tunceli Public Hospital, Tunceli
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/NSN.NSN_13_20

Rights and Permissions

Objective: Neuropathy is seen in approximately 70% of patients in the predialysis stage; it is more common in individuals with pruritus, which may be an indicator of neuropathy. The aim of this study was to evaluate the presence of neuropathy and pruritus in the predialysis stage. Methods: The study included 60 patients in the predialysis stage and 30 volunteer controls. Neuropathic symptoms and severity and frequency of itching were recorded. The polyneuropathy (PNP) protocol and sympathetic skin responses (SSRs) were examined. Results: Electromyographic PNP was detected in 28.3% of the patients and pruritus in 36.7%. There was no significant difference in terms of neuropathy and SSR between the groups with and without pruritus (P > 0.05). Body mass index (BMI,P < 0.05) and uric acid levels (P = 0.022) were higher in the group with pruritus. The group in the predialysis stage was divided into two groups according to the stages. There was no difference between the groups in terms of neuropathy and pruritus (P > 0.05), whereas the amplitude and velocity of the median nerve, amplitude and velocity of the tibial nerve, amplitude of the sural nerve, and velocity of the peroneal nerve motor were found to be higher in the control group than in the two groups in the predialysis stage. Furthermore, a prolongation of the distal latency median motor nerve was found in two groups in the predialysis stage compared with the control group (P > 0.05). There was no significant difference between the two groups in terms of the presence of neuropathic symptoms and pruritus (P > 0.05). Conclusion: More than one-third (36.7%) of the patients had pruritus. Increased BMI and uric acid levels showed that it could be important to evaluate the patients in the predialysis stage.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed26    
    Printed0    
    Emailed0    
    PDF Downloaded17    
    Comments [Add]    

Recommend this journal